
Guidance for considering and using open literature studies to support human health risk assessment General principles for performing aggregate exposure and risk assessmentsĭetermination of the appropriate FQPA safety factor(s) in tolerance assessmentĬhoosing a percentile of acute dietary exposure as a threshold of regulatory concern Indirect Dietary Residential Exposure Assessment Model (IDREAM) ImplementationĪvailable information on assessing exposure from pesticides in food - A User’s Guideįramework for assessing non-occupational, non-dietary (residential) exposure to pesticides Revised Methods for Worker Risk Assessment Standard operating procedures for residential pesticide exposure assessment Model Statement of Work for RI/FS Baseline Risk Assessments of Human Health Model Site Conceptual Model for RI/FS Baseline Risk Assessments of Human Health Handbook for Non-Cancer Health Effects Valuation Guidance on Cumulative Risk Assessment: Planning & Scoping (Part 1)ĭioxin Toxicity Equivalency Factors (TEFs) for Human HealthĮPA Positive Matrix Factorization (PMF) 5.0 Fundamentals and User GuideĮPA's Strategic Plan for Evaluating the Toxicity of ChemicalsĮstimating Site-Specific Exposure to Contaminants in Indoor DustĮvaluating and Identifying Contaminants of Concern for Human HealthĮxploration of Perinatal Pharmacokinetic Issues Technical Guidance, BMDS, Modeling, AssessmentsĬonflicts of Interest Review Process for Contractor-Managed Peer Reviews of EPA Highly Influential Scientific Assessment (HISA) and Influential Scientific Information (ISI) DocumentsĬonsiderations for Developing a Dosimetry-Based Cumulative Risk Assessment Approach for Mixtures of Environmental ContaminantsĬriteria for Evaluating Blood Lead Data Quality and UseĬumulative Health Risk Assessment of Multiple Chemicals, Exposures, and Effects: A Resource Document Summary Report, Human Health, Exposure FactorsĪssessment of Thyroid Follicular Cell Tumors Guidance Document, Human Health, RFD, RFCĪlpha2u-Globulin: Association with Chemically Induced Renal Toxicity and Neoplasia in the Male RatĪ Summary of General Assessment Factors for Evaluating the Quality of Scientific and Technical Information Guidance Document, Human Health, ChildrenĪ Framework for Assessing Health Risk of Environmental Exposures to ChildrenĪ Review of the Reference Dose and Reference Concentration Processes Guidelines for the Health Risk Assessment of Chemical Mixtures Guidance Document, Human Health, Chemical Mixtures Guidelines for Mutagenicity Risk Assessment Guidance Document, Human Health, Developmental Toxicity Guidelines for Developmental Toxicity Risk Assessment Guidance Document, Human Health, Exposure Guidance Document, Reproductive Toxicity, Human Health Guidelines for Reproductive Toxicity Risk Assessment Guiding Principles for Monte Carlo Analysis Guidance Document, Neurotoxicity, Human Health Guidelines for Neurotoxicity Risk Assessment Guidance on Cumulative Risk Assessment of Pesticides with a Common Mechanism of ToxicityĮPA Methodology for Deriving Ambient Water Quality Criteria for the Protection of Human Health

Supplemental Guidance for Assessing Susceptibility from Early-Life Exposure to Carcinogens Guidelines for Carcinogen Risk Assessment

Guidance on Selecting Age Groups for Monitoring and Assessing Childhood Exposures to Environmental Contaminants Guide to Considering Children's Health When Developing EPA Actions: Implementing Executive Order 13045 and EPA's Policy on Evaluating Health Risks to Children Scientific and Ethical Approaches to Observational Exposure Studies (SEAOES) Guidance Document, Human Health, Pathogens Guideline for Microbial Risk Assessment: Pathogenic Microorganisms with Focus on Food and Water Probabilistic Risk Assessment White Paper Guidance Document, Toxicokinetic, Toxicodynamicįramework for Human Health Risk Assessment to Inform Decision Making Guidance for Applying Quantitative Data to Develop Data-Derived Extrapolation Factors for Interspecies and Intraspecies Extrapolation TitleĬumulative Risk Assessment Lessons Learned: A Review of Case Studies and Issue Papers The following tables includes guidance documents, handbooks, framework documents, standard operating procedures (SOPs), and other related materials developed by EPA for human health risk assessments.
